Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823636 | 0.92 | PARP10 (0.74) | PARP10MAPTLMNAESR1ESR2 | |
| Hydroquinone SCHEMBL8674228 | 0.92 | PARP10 (0.74) | PARP10MAPTLMNAESR1ESR2 | |
| SCHEMBL162830 | 0.92 | PARP10 (0.74) | PARP10MAPTLMNAESR1ESR2 | |
| Hydrochloric Acid SCHEMBL3139339 | 0.90 | PARP10 (0.71) | PARP10MAPTLMNAESR1ESR2 | |
| Ammonia Solution, Strong SCHEMBL28805645 | 0.90 | PARP10 (0.71) | PARP10MAPTLMNAESR1ESR2 | |
| SCHEMBL28831945 | 0.90 | PARP10 (0.71) | PARP10MAPTLMNAESR1ESR2 | |
| Methane SCHEMBL28048015 | 0.90 | PARP10 (0.71) | PARP10MAPTLMNAESR1ESR2 | |
| Terephthalamide SCHEMBL12613686 | 0.89 | PARP1 (0.60) | PARP10MAPTCA2PARP1CA1 | |
| Terephthalamide SCHEMBL472214 | 0.89 | PARP1 (0.60) | PARP10MAPTCA2PARP1CA1 | |
| Terephthalamide SCHEMBL197479 | 0.89 | PARP1 (0.60) | PARP10MAPTCA2PARP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4221703-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |