Terephthalamide

Terephthalamide

SCHEMBL472214

C1CCC1.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.60
TSHR P16473 2/20 0.60
POLB P06746 1/20 0.60
CYP3A4 P08684 1/20 0.60
MAPT P10636 1/20 0.60
CYP2C19 P33261 1/20 0.60
RECQL P46063 1/20 0.60
BLM P54132 1/20 0.60
PMP22 Q01453 1/20 0.60
HSD17B10 Q99714 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
PARP10 Q53GL7 11/20 0.59
PARP15 Q460N3 5/20 0.59
PARP4 Q9UKK3 2/20 0.59
ALDH1A1 P00352 1/20 0.59
KMT2A Q03164 1/20 0.59
PARP14 Q460N5 1/20 0.59
PARP16 Q8N5Y8 1/20 0.59
PARP11 Q9NR21 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL12613686 1.00 PARP1 (0.60) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL197479 1.00 PARP1 (0.60) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL4131585 0.97 PARP1 (0.57) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL23774 0.90 PARP1 (0.71) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL25338154 0.89 PARP10 (0.65) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL11512422 0.87 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL15328883 0.87 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL1906838 0.87 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL1087289 0.87 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL689841 0.87 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101987915-B Polymer composite containing polyalcohol and co-stabilizer DU PONT 2012-09-05 CN claimed
EP-1226202-B1 COPOLYAMIDE BASED ON TETRAMETHYLENE TEREPHTHALAMIDE AND HEXAMETHYLENE TEREPHTHALAMIDE DSM IP ASSETS BV (NL) 2006-06-07 EP claimed
US-6747120-B2 COPOLYMER HAS MELTING POINT HIGHER THAN 290 DEGREES CELCIUS, HIGH CRYSTALLINITY AND GOOD DIMENSIONAL STABILITY DSM IP ASSETS B.V. (NL) 2004-06-08 US claimed
JP-2003528165-A 2003-09-24 JP claimed
US-20020183479-A1 Copolyamide based on tetramethylene terephthalamide and hexamethylene tereohthalamide DSM IP ASSETS B.V. (NL) 2002-12-05 US claimed
EP-1226202-A1 COPOLYAMIDE BASED ON TETRAMETHYLENE TEREPHTHALAMIDE AND HEXAMETHYLENE TEREPHTHALAMIDE DSM N.V. (NL) 2002-07-31 EP claimed
WO-2001025311-A1 COPOLYAMIDE BASED ON TETRAMETHYLENE TEREPHTHALAMIDE AND HEXAMETHYLENE TEREPHTHALAMIDE DSM N.V. (NL) 2001-04-12 WO claimed
EP-0411709-B1 Polyamide composition DSM NV (NL) 1994-06-01 EP claimed
US-5084552-A Tetramethylenediamine with adipic acid, terephthalic acid and isophthalic acid terpolyamide for moldings and films STAMICARBON B.V. (NL) 1992-01-28 US claimed
EP-0411709-A1 Polyamide composition DSM N.V. (NL) 1991-02-06 EP claimed
CN-111225940-B Polymerization process 杜邦聚合物公司 2023-10-10 CN disclosed
WO-2023182252-A1 ROLLER-BEARING RETAINER AND ROLLER BEARING NTN株式会社 2023-09-28 WO disclosed
EP-3524718-B1 RAW YARN FOR AIR BAG, AND METHOD FOR PRODUCE OF THE RAW YARN TORAY INDUSTRIES (JP) 2023-07-12 EP disclosed
US-11578171-B2 Thermoplastic composition, molded part made thereof and use thereof in automotive and E and E applications DSM IP ASSETS B.V. (NL) 2023-02-14 US disclosed
CN-111183174-B Glass fiber reinforced resin molded article 日东纺绩株式会社 2022-10-04 CN disclosed
EP-0411709-B1 Polyamide composition DSM NV (NL) 1994-06-01 EP disclosed
US-5179175-A Impact strength TEXACO CHEMICAL COMPANY (US) 1993-01-12 US disclosed
EP-0490482-A2 Polyamides from polyetheramines, hexamethylene diamine and adipic acid Huntsman Corporation (US) 1992-06-17 EP disclosed
US-5084552-A Tetramethylenediamine with adipic acid, terephthalic acid and isophthalic acid terpolyamide for moldings and films STAMICARBON B.V. (NL) 1992-01-28 US disclosed
EP-0411709-A1 Polyamide composition DSM N.V. (NL) 1991-02-06 EP disclosed