SCHEMBL28823636

SCHEMBL28823636

NC(=O)c1ccc(O)cc1.NC(=O)c1ccc(O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.74
MAPT P10636 2/20 0.60
LMNA P02545 2/20 0.60
ESR1 P03372 1/20 0.60
ESR2 Q92731 1/20 0.60
PKM P14618 1/20 0.60
HPGD P15428 1/20 0.60
HTT P42858 1/20 0.60
CA2 P00918 4/20 0.57
CA1 P00915 3/20 0.57
PARP1 P09874 3/20 0.57
CYP3A4 P08684 2/20 0.57
BLM P54132 2/20 0.57
PMP22 Q01453 2/20 0.57
TSHR P16473 2/20 0.57
POLB P06746 1/20 0.57
CYP2C19 P33261 1/20 0.57
RECQL P46063 1/20 0.57
HSD17B10 Q99714 1/20 0.57
TDP1 Q9NUW8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162830 1.00 PARP10 (0.74) PARP10MAPTLMNAESR1ESR2
Hydroquinone SCHEMBL8674228 1.00 PARP10 (0.74) PARP10MAPTLMNAESR1ESR2
Hydrochloric Acid SCHEMBL3139339 0.97 PARP10 (0.71) PARP10MAPTLMNAESR1ESR2
Methane SCHEMBL28048015 0.97 PARP10 (0.71) PARP10MAPTLMNAESR1ESR2
Ammonia Solution, Strong SCHEMBL28805645 0.97 PARP10 (0.71) PARP10MAPTLMNAESR1ESR2
SCHEMBL28831945 0.97 PARP10 (0.71) PARP10MAPTLMNAESR1ESR2
SCHEMBL25338154 0.92 PARP10 (0.65) PARP10MAPTLMNAESR1ESR2
SCHEMBL1791123 0.92 PARP10 (0.65) PARP10MAPTLMNAESR1ESR2
SCHEMBL4300988 0.90 PARP10 (0.63) PARP10MAPTLMNAESR1ESR2
Benzamide SCHEMBL10890603 0.90 MAPT (0.76) PARP10MAPTLMNAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104995289-A Lubricant composition including 4-hydroxybenzamide friction modifier LUBRIZOL CORP 2015-10-21 CN disclosed