⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973876 | 0.81 | CCR5 (0.40) | — | |
| SCHEMBL25338364 | 0.81 | CCR5 (0.40) | — | |
| SCHEMBL26644694 | 0.78 | SSTR1 (0.37) | — | |
| SCHEMBL25337092 | 0.78 | SSTR1 (0.37) | — | |
| SCHEMBL23536457 | 0.73 | GFER (0.34) | — | |
| SCHEMBL26766523 | 0.70 | CCR5 (0.41) | — | |
| SCHEMBL25340159 | 0.70 | CCR5 (0.41) | — | |
| SCHEMBL25339143 | 0.68 | ACHE (0.30) | — | |
| SCHEMBL25339080 | 0.68 | — | — | |
| SCHEMBL23536513 | 0.68 | USP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365562-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-11-16 | — | — | US | disclosed |
| WO-2023147594-A2 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |