Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626439 | 0.95 | RORC (0.33) | RORCCA1CA2ACHEPDE4B | |
| SCHEMBL25339147 | 0.85 | CA1 (0.39) | RORCKEAP1NFE2L2CA1CA2 | |
| SCHEMBL25340296 | 0.82 | RORC (0.36) | RORCKEAP1NFE2L2CA1CA2 | |
| SCHEMBL25339577 | 0.82 | CYP2C9 (0.32) | RORCPDE4B | |
| SCHEMBL25339103 | 0.81 | ACACB (0.33) | RORCKEAP1NFE2L2CA1CA2 | |
| SCHEMBL25337797 | 0.81 | RORC (0.34) | RORCKEAP1NFE2L2CA1 | |
| SCHEMBL29626395 | 0.81 | CA1 (0.38) | RORCCA1CA2ACHEPDE4B | |
| SCHEMBL25339196 | 0.81 | RORC (0.35) | RORCKEAP1NFE2L2 | |
| SCHEMBL25241594 | 0.81 | RORC (0.36) | RORCKEAP1NFE2L2CA1CA2 | |
| SCHEMBL22412394 | 0.79 | CA1 (0.43) | KEAP1NFE2L2CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4211122-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Calico Life Sciences LLC (US) | 2023-07-19 | — | — | EP | disclosed |