SCHEMBL25339147 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CA1	P00915	3/20	0.39

▸	CA2	P00918	3/20	0.39

▸	ACHE	P22303	3/20	0.39

▸	RORC	P51449	6/20	0.36

▸	KEAP1	Q14145	8/20	0.33

▸	NFE2L2	Q16236	8/20	0.33

▸	L3MBTL1	Q9Y468	2/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	PDE4B	Q07343	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29626395	0.95	CA1 (0.38)	CA1CA2ACHERORCL3MBTL1
SCHEMBL22412394	0.94	CA1 (0.43)	CA1CA2ACHEKEAP1NFE2L2
SCHEMBL29024337	0.93	CA1 (0.41)	CA1CA2ACHERORCL3MBTL1
SCHEMBL29626474	0.93	CA1 (0.41)	CA1CA2ACHERORCL3MBTL1
SCHEMBL25339103	0.90	ACACB (0.33)	CA1CA2ACHERORCKEAP1
SCHEMBL25241594	0.89	RORC (0.36)	CA1CA2ACHERORCKEAP1
SCHEMBL25340296	0.88	RORC (0.36)	CA1CA2ACHERORCKEAP1
SCHEMBL22412558	0.87	CA1 (0.30)	CA1CA2ACHE
SCHEMBL29626309	0.85	ACACB (0.33)	CA1CA2ACHERORCKMT2A
SCHEMBL25338458	0.85	RORC (0.33)	CA1CA2ACHERORCKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4211122-A1	PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF	Calico Life Sciences LLC (US)	2023-07-19	—	—	EP	disclosed