Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339489 | 0.77 | ADRB2 (0.42) | ADRB2OPRM1HSD11B1DAOALDH1A1 | |
| SCHEMBL25339124 | 0.74 | ADRB2 (0.39) | ADRB2OPRM1HSD11B1ALDH1A1 | |
| SCHEMBL25335842 | 0.74 | ADRB2 (0.39) | ADRB2OPRM1HSD11B1ALDH1A1 | |
| SCHEMBL25339786 | 0.73 | ADRB2 (0.39) | ADRB2OPRM1HSD11B1DAO | |
| SCHEMBL2242113 | 0.72 | RIPK1 (0.48) | — | |
| SCHEMBL30543622 | 0.72 | PARP1 (0.41) | ADRB2OPRM1KDM4E | |
| SCHEMBL25339597 | 0.72 | PARP1 (0.41) | ADRB2OPRM1KDM4E | |
| SCHEMBL31211804 | 0.72 | DDB1 (0.38) | ADRB2OPRM1HSD11B1ALDH1A1 | |
| SCHEMBL25339372 | 0.69 | DAO (0.38) | ADRB2OPRM1DAO | |
| SCHEMBL25339303 | 0.69 | PARP1 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365562-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-11-16 | — | — | US | disclosed |
| WO-2023147594-A2 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365562-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | ADRB2 4578/4885OPRM1 4472/4885HSD11B1 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.