Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132486 | 0.92 | KEAP1 (0.41) | MEN1KMT2ALMNACA1CA2 | |
| SCHEMBL25338513 | 0.88 | BRD4 (0.37) | MEN1ALDH1A1KMT2ASGMS2BRD4 | |
| SCHEMBL25338586 | 0.83 | ITGB3 (0.43) | MEN1ALDH1A1KMT2A | |
| SCHEMBL22412174 | 0.80 | CA1 (0.44) | MEN1ALDH1A1KMT2ASGMS2MTNR1A | |
| SCHEMBL29132508 | 0.80 | PTGIR (0.38) | LMNACA1CA2ACHE | |
| SCHEMBL30683967 | 0.80 | PTGIR (0.38) | LMNACA1CA2ACHE | |
| SCHEMBL29626301 | 0.80 | ACACB (0.41) | BRD4 | |
| SCHEMBL25336821 | 0.77 | PTGIR (0.37) | MEN1ALDH1A1KMT2ALRRK2L3MBTL1 | |
| SCHEMBL28934875 | 0.76 | CA1 (0.56) | MEN1ALDH1A1KMT2ASGMS2CA1 | |
| Hydrochloric Acid SCHEMBL22412455 | 0.74 | KDM1A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4211122-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Calico Life Sciences LLC (US) | 2023-07-19 | — | — | EP | disclosed |