⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695625 | 0.80 | TRPA1 (0.36) | — | |
| SCHEMBL1076726 | 0.78 | — | — | |
| SCHEMBL9309534 | 0.76 | — | — | |
| SCHEMBL4602076 | 0.76 | — | — | |
| SCHEMBL4619141 | 0.76 | — | — | |
| SCHEMBL2723461 | 0.74 | — | — | |
| Charcoal, Activated SCHEMBL9337856 | 0.74 | TRPA1 (0.32) | — | |
| SCHEMBL11132967 | 0.71 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL17035614 | 0.71 | TSHR (0.40) | — | |
| SCHEMBL15068262 | 0.71 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232997-A | Mercapto-substituted monovalent hydrocarbon groups bonded to silicon atoms | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-08-03 | — | — | US | claimed |
| EP-2064251-B1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KENSEY NASH CORP (US) | 2017-10-25 | — | — | EP | disclosed |
| EP-2334305-B1 | BIOADHESIVE CONSTRUCTS | KENSEY NASH CORP (US) | 2015-04-22 | — | — | EP | disclosed |
| US-8575276-B2 | Biomimetic compounds and synthetic methods therefor | KNC NER ACQUISITION SUB, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-8383092-B2 | Bioadhesive constructs | KNC NER ACQUISITION SUB, INC. (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120078296-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KNC NER ACQUISITION SUB, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120003888-A1 | BIOADHESIVE CONSTRUCTS WITH POLYMER BLENDS | KNC NER ACQUISITION SUB, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-8030413-B2 | Biomimetic compounds and synthetic methods therefor | KNC NER ACQUISITION SUB, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| EP-2334305-A1 | BIOADHESIVE CONSTRUCTS | KNC NER Acquisition Sub, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010091300-A1 | BIOADHESIVE CONSTRUCTS WITH POLYMER BLENDS | NERITES CORPORATION (US) | 2010-08-12 | — | — | WO | disclosed |
| US-20100137903-A1 | BIOADHESIVE CONSTRUCTS | NERITES CORPORATION (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100137902-A1 | BIOADHESIVE CONSTRUCTS | NERITES CORPORATION (US) | 2010-06-03 | — | — | US | disclosed |
| WO-2010037044-A1 | BIOADHESIVE CONSTRUCTS | NERITES CORPORATION (US) | 2010-04-01 | — | — | WO | disclosed |
| US-7622533-B2 | Biomimetic compounds and synthetic methods therefor | NERITES CORPORATION (US) | 2009-11-24 | — | — | US | disclosed |
| US-20090076241-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION | 2009-03-19 | — | — | US | disclosed |
| US-20080171836-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KENSEY NASH CORPORATION | 2008-07-17 | — | — | US | disclosed |
| EP-0366558-B1 | Rubber composition | NISSIN CHEMICAL IND (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5232997-A | Mercapto-substituted monovalent hydrocarbon groups bonded to silicon atoms | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| US-5059648-A | Reinforcing filler for improved flowability and workability; molding materials | NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0366558-A1 | Rubber composition | NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |