SCHEMBL2534161

SCHEMBL2534161

[CH2]CCCC(C#N)CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2537867 0.93 TSHR (0.30)
SCHEMBL145293 0.91
SCHEMBL2539088 0.87
SCHEMBL2541682 0.83 TSHR (0.35)
SCHEMBL15309950 0.81 TSHR (0.41)
SCHEMBL364917 0.80 TSHR (0.32)
SCHEMBL3671291 0.79
SCHEMBL8960289 0.78
SCHEMBL1960012 0.77 TSHR (0.43)
SCHEMBL15309753 0.77 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8044070-B2 Heteroaryloxy nitrogenous saturated heterocyclic derivative MSD K.K. (JP) 2011-10-25 US disclosed
US-7790897-B2 Graftable hindered amine light stabilizers CIBA SPECIALTY CHEMICALS CORP. (US) 2010-09-07 US disclosed
US-20100210637-A1 HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE MSD K.K. (JP) 2010-08-19 US disclosed
US-7595316-B2 Heteroaryloxy nitrogenous saturated heterocyclic derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2009-09-29 US disclosed
US-20090144915-A1 Graftable hindered amine light stabilizers MEIER HANS-RUDOLF 2009-06-11 US disclosed
US-7504510-B2 Graftable hindered amine light stabilizers CIBA SPECIALTY CHEMICALS CORP. (US) 2009-03-17 US disclosed
EP-1592664-B1 GRAFTABLE HINDERED AMINE LIGHT STABILIZERS CIBA SC HOLDING AG (CH) 2006-08-23 EP disclosed
US-20060178375-A1 Heteroaryloxy nitrogenous saturated heterocyclic derivative MSD K.K. (JP) 2006-08-10 US disclosed
US-20060173107-A1 Graftable hindered amine light stabilizers CIBA SPECIALTY CHEMICALS CORP. 2006-08-03 US disclosed
EP-1642898-A1 HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-04-05 EP disclosed
EP-1592664-A1 GRAFTABLE HINDERED AMINE LIGHT STABILIZERS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072035-A1 GRAFTABLE HINDERED AMINE LIGHT STABILIZERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed
EP-0322003-A2 Azomethine dye derived from a compound having a pyrazolo triazole moiety FUJI PHOTO FILM CO., LTD. (JP) 1989-06-28 EP disclosed
EP-0104590-B1 PHOTOCURABLE SILICON COMPOUND COMPOSITION KABUSHIKI KAISHA TOSHIBA (JP) 1987-04-08 EP disclosed
US-4476290-A Photocurable silicon compound composition TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1984-10-09 US disclosed
EP-0119860-A2 Pyrazolo magenta couplers used in silver halide photography FUJI PHOTO FILM CO., LTD. (JP) 1984-09-26 EP disclosed
EP-0104590-A1 Photocurable silicon compound composition KABUSHIKI KAISHA TOSHIBA (JP) 1984-04-04 EP disclosed