Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145293 | 0.98 | — | — | |
| SCHEMBL2534161 | 0.93 | — | — | |
| SCHEMBL2539088 | 0.85 | — | — | |
| SCHEMBL4354552 | 0.82 | — | — | |
| SCHEMBL6050196 | 0.82 | TSHR (0.37) | TSHR | |
| SCHEMBL6050201 | 0.82 | TSHR (0.37) | TSHR | |
| SCHEMBL29102703 | 0.82 | TSHR (0.37) | TSHR | |
| SCHEMBL6050246 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL1960012 | 0.80 | TSHR (0.43) | TSHR | |
| SCHEMBL15309950 | 0.79 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044070-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-7790897-B2 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20100210637-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | MSD K.K. (JP) | 2010-08-19 | — | — | US | disclosed |
| US-7595316-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-29 | — | — | US | disclosed |
| US-20090144915-A1 | Graftable hindered amine light stabilizers | MEIER HANS-RUDOLF | 2009-06-11 | — | — | US | disclosed |
| US-7504510-B2 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-03-17 | — | — | US | disclosed |
| EP-1592664-B1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | CIBA SC HOLDING AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| US-20060178375-A1 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2006-08-10 | — | — | US | disclosed |
| US-20060173107-A1 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2006-08-03 | — | — | US | disclosed |
| EP-1642898-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090144915-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, AOX1 | TSHR 3638/4885 |
| US-20060173107-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, TPH1 | TSHR 3853/4885 |
| US-20060178375-A1 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | HRH3, HRH4, HCRTR2 | TSHR 226/4885 |
| US-20100210637-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | HRH3, HRH4, HRH2 | TSHR 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.