Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568630 | 1.00 | USP30 (0.34) | USP30MEN1POLBKMT2APDK2 | |
| SCHEMBL25343427 | 0.90 | USP30 (0.36) | USP30PDK2GBA1 | |
| SCHEMBL30568626 | 0.90 | USP30 (0.36) | USP30PDK2GBA1 | |
| SCHEMBL30568483 | 0.89 | USP30 (0.35) | USP30PDK2LMNAGBA1 | |
| SCHEMBL25346349 | 0.89 | USP30 (0.35) | USP30PDK2LMNAGBA1 | |
| SCHEMBL25344607 | 0.82 | USP30 (0.35) | USP30 | |
| SCHEMBL30568453 | 0.82 | USP30 (0.35) | USP30 | |
| SCHEMBL25343953 | 0.81 | USP30 (0.33) | USP30SMN1; SMN2 | |
| SCHEMBL30568503 | 0.81 | USP30 (0.33) | USP30SMN1; SMN2 | |
| SCHEMBL25343527 | 0.81 | USP30 (0.34) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148129-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-10 | — | — | WO | disclosed |