Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30479647 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBTSHRSLC6A2 | |
| SCHEMBL25980663 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBTSHRSLC6A2 | |
| SCHEMBL25345233 | 0.78 | POLB (0.43) | ALDH1A1KDM4EPOLBTSHRSLC6A2 | |
| SCHEMBL6600294 | 0.75 | MAPT (0.43) | ALDH1A1KDM4EPOLBTSHRSLC6A2 | |
| SCHEMBL25341773 | 0.74 | GAA (0.40) | ALDH1A1KDM4EPOLBTSHRSLC6A2 | |
| SCHEMBL15602928 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBTSHRMEN1 | |
| SCHEMBL2550348 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBTSHRMEN1 | |
| SCHEMBL2547103 | 0.72 | ALDH1A1 (0.53) | ALDH1A1KDM4EPOLBTSHRMEN1 | |
| SCHEMBL15670616 | 0.71 | KMT2A (0.49) | ALDH1A1KDM4EPOLBTSHRMEN1 | |
| SCHEMBL2551664 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBTSHRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |