Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30479647 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4ETDP1GAASLC6A2 | |
| SCHEMBL25342155 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1GAASLC6A2 | |
| SCHEMBL24743093 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1GAASLC6A2 | |
| SCHEMBL192119 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1GAALMNA | |
| SCHEMBL31564004 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4ETDP1LMNAMEN1 | |
| SCHEMBL25980674 | 0.79 | GAA (0.39) | ALDH1A1KDM4ETDP1GAASLC6A2 | |
| SCHEMBL5383935 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1KDM4EGAALMNAMEN1 | |
| SCHEMBL14680120 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1GAASLC6A2 | |
| SCHEMBL15624358 | 0.78 | KMT2A (0.55) | ALDH1A1KDM4ETDP1GAALMNA | |
| SCHEMBL12282460 | 0.77 | MEN1 (0.43) | ALDH1A1KDM4ETDP1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |