Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 18/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31181401 | 1.00 | TLR8 (0.52) | TLR8TLR7SCN9APKM | |
| SCHEMBL25345043 | 0.91 | TLR8 (0.55) | TLR8TLR7PKM | |
| SCHEMBL25344703 | 0.87 | TLR8 (0.49) | TLR8TLR7 | |
| SCHEMBL25344867 | 0.85 | TLR8 (0.52) | TLR8TLR7 | |
| SCHEMBL31506972 | 0.84 | TLR8 (0.43) | TLR8TLR7PKM | |
| SCHEMBL25345573 | 0.84 | TLR8 (0.47) | TLR8TLR7 | |
| SCHEMBL25345721 | 0.84 | TLR8 (0.49) | TLR8TLR7 | |
| SCHEMBL25343868 | 0.82 | TLR8 (0.42) | TLR8SCN9APKM | |
| SCHEMBL25342403 | 0.80 | TLR8 (0.59) | TLR8TLR7 | |
| SCHEMBL27078289 | 0.79 | TLR8 (0.49) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154307-A1 | ANTIBODY-CONJUGATED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023154302-A1 | MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |