Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 17/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31506979 | 0.88 | TLR8 (0.43) | TLR8TLR7 | |
| SCHEMBL25345968 | 0.88 | TLR8 (0.43) | TLR8TLR7 | |
| SCHEMBL31506977 | 0.87 | TLR8 (0.44) | TLR8TLR7 | |
| SCHEMBL31181401 | 0.84 | TLR8 (0.52) | TLR8PKMTLR7 | |
| SCHEMBL25342291 | 0.84 | TLR8 (0.52) | TLR8PKMTLR7 | |
| SCHEMBL24698699 | 0.84 | TLR8 (0.42) | TLR8TLR7 | |
| SCHEMBL31051342 | 0.84 | TLR8 (0.42) | TLR8TLR7 | |
| SCHEMBL30945303 | 0.84 | TLR8 (0.40) | TLR8TLR7 | |
| SCHEMBL24698496 | 0.83 | TLR8 (0.42) | TLR8TLR7 | |
| SCHEMBL25344536 | 0.83 | TLR8 (0.54) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145575-A1 | MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2025-05-08 | — | — | US | disclosed |
| US-20250127914-A1 | ANTIBODY-CONJUGATED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BOLT BIOTHERAPEUTICS, INC. (US) | 2025-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145575-A1 | MACROMOLECULE-SUPPORTED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BRD4, MUS81, ABCC8 | TLR8 1341/4885PKM 277/4885TDP1 2929/4885 |
| US-20250127914-A1 | ANTIBODY-CONJUGATED 8-SULFONYL-BENZAZEPINE COMPOUNDS AND THEIR USES | BCR, CD22, IGSF11 | TLR8 851/4885PKM 3317/4885TDP1 4653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.