Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | ADCYAP1R1 | P41586 | 3/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684865 | 0.80 | KDM4E (0.74) | KDM4EMEN1KMT2ANPC1USP2 | |
| SCHEMBL685046 | 0.72 | KDM1A (0.52) | KDM4EMEN1KMT2ANPC1USP2 | |
| SCHEMBL686246 | 0.72 | SIRT1 (0.61) | KDM4EMEN1KMT2ANPC1USP2 | |
| SCHEMBL684624 | 0.71 | SIRT1 (0.77) | KDM4EMEN1KMT2ANPC1USP2 | |
| SCHEMBL2474636 | 0.71 | SPHK2 (0.47) | KDM4EMEN1KMT2ANPC1TDP1 | |
| SCHEMBL9921127 | 0.70 | SIRT1 (0.61) | KDM4EMEN1KMT2ANPC1USP2 | |
| SCHEMBL683833 | 0.70 | KDM4E (0.67) | KDM4EMEN1KMT2ANPC1USP2 | |
| SCHEMBL5815125 | 0.69 | ALDH1A1 (0.50) | KDM4EMEN1KMT2ANPC1TDP1 | |
| SCHEMBL684540 | 0.69 | KDM1A (0.77) | KDM4EMEN1KMT2ANPC1TDP1 | |
| SCHEMBL684848 | 0.69 | NPC1 (0.75) | KDM4EMEN1KMT2ANPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376438-A2 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | Dow AgroSciences LLC (US) | 2011-10-19 | — | — | EP | disclosed |