Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22764833 | 0.88 | APP (0.48) | APPBCHEACHEALDH1A1TSHR | |
| SCHEMBL390876 | 0.85 | ALDH1A1 (0.52) | APPBCHEACHEALDH1A1TSHR | |
| SCHEMBL30085363 | 0.85 | ALDH1A1 (0.52) | APPBCHEACHEALDH1A1TSHR | |
| SCHEMBL18905642 | 0.85 | APP (0.51) | APPALDH1A1TSHRNPC1MAPT | |
| SCHEMBL1268756 | 0.83 | ALDH1A1 (0.50) | BCHEACHEALDH1A1TSHRKDM4E | |
| SCHEMBL31726567 | 0.83 | ALDH1A1 (0.50) | BCHEACHEALDH1A1TSHRKDM4E | |
| SCHEMBL13228861 | 0.83 | APP (0.50) | APPALDH1A1TSHRMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL11291701 | 0.81 | ALDH1A1 (0.48) | BCHEACHEALDH1A1TSHRKDM4E | |
| SCHEMBL5669695 | 0.80 | BCHE (0.53) | APPBCHEACHEALDH1A1TSHR | |
| SCHEMBL8310971 | 0.80 | TSHR (0.52) | APPALDH1A1TSHRKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | OREGON HEALTH & SCIENCE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | OREGON HEALTH & SCIENCE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | OREGON HEALTH & SCIENCE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| EP-4225122-A1 | ZWITTERIONIC CELL-PERMEANT AND WATER-SOLUBLE RHODAMINE DYES FOR QUANTITATIVE IMAGING APPLICATIONS | Oregon Health & Science University (US) | 2023-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | SLC1A5, SLCO1B1, SLCO2B1 | APP 1181/4885BCHE 2914/4885ACHE 3147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.