SCHEMBL390876

SCHEMBL390876

CN(C)c1cccc(Oc2cccc(N(C)C)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
APP P05067 2/20 0.51
BCHE P06276 2/20 0.49
ACHE P22303 1/20 0.49
HRH4 Q9H3N8 1/20 0.46
F2 P00734 1/20 0.44
F10 P00742 1/20 0.44
FFAR1 O14842 1/20 0.44
HSD17B1 P14061 2/20 0.44
HSD17B2 P37059 2/20 0.44
CETP P11597 1/20 0.43
CHEK2 O96017 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
MEN1 O00255 1/20 0.41
MITF O75030 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
GFER P55789 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30085363 1.00 ALDH1A1 (0.52) ALDH1A1TSHRAPPBCHEACHE
SCHEMBL5669695 0.94 BCHE (0.53) ALDH1A1TSHRAPPBCHEACHE
SCHEMBL20838956 0.90 SMN1; SMN2 (0.55) ALDH1A1TSHRAPPACHEHSD17B1
SCHEMBL30053811 0.90 SMN1; SMN2 (0.55) ALDH1A1TSHRAPPACHEHSD17B1
SCHEMBL15474243 0.88 HSD17B1 (0.51) ALDH1A1TSHRAPPBCHEACHE
SCHEMBL5954479 0.87 ALDH1A1 (0.66) ALDH1A1TSHRAPPFFAR1HSD17B1
SCHEMBL12260636 0.87 APP (0.44) ALDH1A1TSHRAPPBCHEACHE
SCHEMBL2397944 0.87 APP (0.44) ALDH1A1TSHRAPPBCHEACHE
SCHEMBL24074788 0.85 NPBWR1 (0.48) ALDH1A1TSHRAPPBCHEACHE
SCHEMBL28967632 0.85 NR4A1 (0.59) ALDH1A1TSHRAPPBCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303150-B High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2021-10-19 CN disclosed
CN-111303150-A High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2020-06-19 CN disclosed
US-10274874-B2 Intermediate transfer member, method for producing intermediate transfer member, and image forming apparatus Konica Minolta, Inc. (JP) 2019-04-30 US disclosed
US-20180136590-A1 INTERMEDIATE TRANSFER MEMBER, METHOD FOR PRODUCING INTERMEDIATE TRANSFER MEMBER, AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2018-05-17 US disclosed
US-20180136590-A1 INTERMEDIATE TRANSFER MEMBER, METHOD FOR PRODUCING INTERMEDIATE TRANSFER MEMBER, AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2018-05-17 US disclosed
US-8101655-B2 Fluorescent dyes and complexes SMITH GERALD ARTHUR (GB) 2012-01-24 US disclosed
US-8101655-B2 Fluorescent dyes and complexes SMITH GERALD ARTHUR (GB) 2012-01-24 US disclosed
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-10-07 US disclosed
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-10-07 US disclosed
US-7674918-B2 Fluorescent dyes and complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-03-09 US disclosed
US-7674918-B2 Fluorescent dyes and complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-03-09 US disclosed
US-20070238884-A1 Fluorescent Dyes and Complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-11 US disclosed
US-20070238884-A1 Fluorescent Dyes and Complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238884-A1 Fluorescent Dyes and Complexes F12, PYM1, ANXA6 ALDH1A1 1039/4885TSHR 1099/4885APP 1841/4885
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES F12, ANXA6, PYM1 ALDH1A1 1468/4885TSHR 1171/4885APP 1953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.