Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568608 | 1.00 | PRPS1 (0.42) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL25343063 | 0.92 | SSTR4 (0.45) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL30568651 | 0.92 | SSTR4 (0.45) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL30568456 | 0.90 | PRPS1 (0.39) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL25343570 | 0.90 | PRPS1 (0.39) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL30568387 | 0.90 | PRPS1 (0.39) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL25344234 | 0.87 | PRPS1 (0.37) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL30568497 | 0.87 | PRPS1 (0.37) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL25345315 | 0.84 | PRPS1 (0.41) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 | |
| SCHEMBL30568545 | 0.84 | PRPS1 (0.41) | PRPS1NPSR1SSTR4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148129-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-10 | — | — | WO | disclosed |