SCHEMBL25344353

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30473743	1.00	PIK3CD (0.46)	PIK3CDMKNK1MKNK2CYP1A2CYP2D6
	SCHEMBL2726056	0.77	CYP1A2 (0.47)	PIK3CDCYP1A2CYP2D6CYP19A1CYP2C9
	SCHEMBL4059081	0.76	CYP1A2 (0.57)	CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
	SCHEMBL390107	0.75	CYP1A2 (0.49)	CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
	SCHEMBL28571256	0.74	ALOX5AP (0.38)	CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
	SCHEMBL1257460	0.73	PIK3CD (0.73)	PIK3CDMKNK1MKNK2CYP1A2KDM4E
	SCHEMBL29740321	0.73	PIK3CD (0.73)	PIK3CDMKNK1MKNK2CYP1A2KDM4E
	SCHEMBL4482799	0.73	CYP1A2 (0.44)	CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
	SCHEMBL13114697	0.73	CYP1A2 (0.51)	CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
	SCHEMBL29544673	0.73	NPC1 (0.51)	MKNK1MKNK2CYP1A2CYP2D6CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.