Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25346516 | 0.85 | CCNT1 (0.35) | CCNT1CDK9KIT | |
| SCHEMBL25345716 | 0.79 | CCNT1 (0.36) | CCNT1CDK9 | |
| SCHEMBL30519541 | 0.73 | MKNK1 (0.40) | — | |
| SCHEMBL26024816 | 0.73 | MKNK1 (0.40) | — | |
| SCHEMBL25345237 | 0.73 | TRPA1 (0.36) | CCNT1CDK9 | |
| SCHEMBL25345643 | 0.72 | TRPA1 (0.35) | CCNT1CDK9 | |
| SCHEMBL30519693 | 0.67 | HASPIN (0.37) | ESR1ALOX5APFEN1HASPIN | |
| SCHEMBL25345628 | 0.65 | S1PR4 (0.37) | HASPIN | |
| SCHEMBL21223595 | 0.65 | MCHR1 (0.47) | CCNT1CDK9MCL1ALOX5APFEN1 | |
| SCHEMBL30172481 | 0.64 | DHODH (0.38) | AAK1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |