Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25345237 | 0.89 | TRPA1 (0.36) | TRPA1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL26025618 | 0.77 | HTR1A (0.38) | TRPA1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL25344697 | 0.72 | CCNT1 (0.35) | CCNT1CDK9 | |
| SCHEMBL25344261 | 0.72 | CRHR1 (0.31) | — | |
| SCHEMBL25346516 | 0.72 | CCNT1 (0.35) | CCNT1CDK9 | |
| SCHEMBL21223595 | 0.70 | MCHR1 (0.47) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL25345716 | 0.70 | CCNT1 (0.36) | CCNT1CDK9 | |
| SCHEMBL25344718 | 0.68 | KDM4E (0.37) | — | |
| SCHEMBL30519477 | 0.65 | TTK (0.37) | TRPA1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL26025619 | 0.65 | TTK (0.37) | TRPA1HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |