Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364257 | 1.00 | EGFR (0.52) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL6364252 | 1.00 | EGFR (0.52) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| Tert-Butylamine SCHEMBL11592411 | 0.93 | EGFR (0.47) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| Tert-Butylamine SCHEMBL11592415 | 0.93 | EGFR (0.47) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL2534565 | 0.89 | EGFR (0.54) | EGFRL3MBTL1GAAALDH1A1HCAR2 | |
| SCHEMBL1700981 | 0.89 | EGFR (0.54) | EGFRL3MBTL1GAAALDH1A1HCAR2 | |
| Fumaric Acid SCHEMBL8645982 | 0.84 | ALDH1A1 (0.43) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| Maleic Acid SCHEMBL8645980 | 0.84 | ALDH1A1 (0.43) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL14751387 | 0.81 | L3MBTL1 (0.47) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL12328701 | 0.78 | L3MBTL1 (0.49) | EGFRL3MBTL1GAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912831-B2 | Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers | ISP INVESTMENTS LLC (US) | 2024-02-27 | — | — | US | disclosed |
| EP-1091929-A2 | SECONDARY ASPARTIC ACID AMIDE ESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001665-A2 | SECONDARY ASPARTIC ACID AMIDE ESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912831-B2 | Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers | MMAB, PCNA, HMBS | EGFR 747/4885L3MBTL1 1589/4885GAA 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.