Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761589 | 1.00 | EGFR (0.52) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL6364252 | 1.00 | EGFR (0.52) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| Tert-Butylamine SCHEMBL11592411 | 0.93 | EGFR (0.47) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| Tert-Butylamine SCHEMBL11592415 | 0.93 | EGFR (0.47) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL2534565 | 0.89 | EGFR (0.54) | EGFRL3MBTL1GAAALDH1A1HCAR2 | |
| SCHEMBL1700981 | 0.89 | EGFR (0.54) | EGFRL3MBTL1GAAALDH1A1HCAR2 | |
| Fumaric Acid SCHEMBL8645982 | 0.84 | ALDH1A1 (0.43) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| Maleic Acid SCHEMBL8645980 | 0.84 | ALDH1A1 (0.43) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL14751387 | 0.81 | L3MBTL1 (0.47) | EGFRL3MBTL1GAAALDH1A1TSHR | |
| SCHEMBL12328701 | 0.78 | L3MBTL1 (0.49) | EGFRL3MBTL1GAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573274-B | Preparation method of heat-resistant modifier N-tert-butyl maleimide | 蔚林新材料科技股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| US-4127617-A | GRAFT POLYMER OF STYRENE-ACRYLONITRILE-A MALEIMIDE ON ETHYLENE-PROPYLENE-DIENE TERPOLYMER | ANIC, S.P.A. (IT) | 1978-11-28 | — | — | US | claimed |
| CN-115784963-B | Method for continuously preparing N-substituted maleimide by utilizing microchannel reactor | 河南省科学院高新技术研究中心 | 2024-11-22 | — | — | CN | disclosed |
| CN-115583907-B | Continuous production process of N-substituted maleimide | 河南省科学院高新技术研究中心 | 2024-09-20 | — | — | CN | disclosed |
| CN-113881118-B | NBR (nitrile butadiene rubber) rubber with low compression set and preparation process thereof | 南阳天一密封股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-115784963-A | Method for continuously preparing N-substituted maleimide by using microchannel reactor | 河南省科学院高新技术研究中心 | 2023-03-14 | — | — | CN | disclosed |
| CN-115583907-A | Continuous production process of N-substituted maleimide | 河南省科学院高新技术研究中心 | 2023-01-10 | — | — | CN | disclosed |
| CN-113881118-A | Low-compression permanent deformation NBR (nitrile-butadiene rubber) material and preparation process thereof | 南阳天一密封股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-107573274-B | Preparation method of heat-resistant modifier N-tert-butyl maleimide | 蔚林新材料科技股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-107573274-B | Preparation method of heat-resistant modifier N-tert-butyl maleimide | 蔚林新材料科技股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| EP-1179024-B1 | ORGANOBORANE AMINE COMPLEX INITIATOR SYSTEMS AND POLYMERIZABLE COMPOSITIONS MADE THEREWITH | 3M INNOVATIVE PROPERTIES CO (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2000001665-A2 | SECONDARY ASPARTIC ACID AMIDE ESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-01-13 | — | — | WO | disclosed |
| US-6005062-A | AND A POLYISOCYANATE COMBINED TO FORM A POLYUREA; TWO PART LIQUID PAVENT MARKING COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0459661-A1 | Silica scale inhibition | ROHM AND HAAS COMPANY (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0080451-B1 | METHOD AND COMPOSITION FOR DIENE RUBBER TREATMENT | MONSANTO COMPANY (US) | 1985-09-18 | — | — | EP | disclosed |
| US-4433114-A | SULFUR OR ORGANOSULFUR COMPOUNDS, MALEAMIC ACID OR DERIVATIVES, TACKINESS, GREEN STRENGTH | MONSANTO COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0080451-A1 | Method and composition for diene rubber treatment | MONSANTO COMPANY (US) | 1983-06-01 | — | — | EP | disclosed |