Sugi Predict

Sugi Predict / Compounds / SCHEMBL2534650

SCHEMBL2534650

SCHEMBL2534650

CC1(C)OC(C(O)(c2ccccc2)c2ccccc2)C(C(O)(c2ccccc2)c2ccccc2)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ MEN1 O00255 3/20 0.58
▸ KMT2A Q03164 3/20 0.58
▸ CYP2C19 P33261 3/20 0.50
▸ LMNA P02545 3/20 0.40
▸ CYP2D6 P10635 2/20 0.40
▸ HRH1 P35367 2/20 0.40
▸ SCN1A P35498 1/20 0.40
▸ SCN2A Q99250 1/20 0.40
▸ SCN3A Q9NY46 1/20 0.40
▸ CHRM3 P20309 1/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ ATM Q13315 1/20 0.38
▸ CYP1A2 P05177 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ APOBEC3A P31941 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7994941 1.00 MAPK1 (1.00) MAPK1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL7916942 1.00 MAPK1 (1.00) MAPK1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL2504692 1.00 MAPK1 (1.00) MAPK1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL4383952 1.00 MAPK1 (1.00) MAPK1CYP3A4MEN1KMT2ACYP2C19
Phosphoric Acid SCHEMBL27782171 0.91 MAPK1 (0.83) MAPK1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL20702246 0.89 MAPK1 (0.80) MAPK1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL19139099 0.89 CYP3A4 (0.79) MAPK1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL3918350 0.89 CYP3A4 (0.79) MAPK1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL16309629 0.87 CYP3A4 (0.77) MAPK1CYP3A4MEN1KMT2ACYP2C19
SCHEMBL8538968 0.82 MAPK1 (0.70) MAPK1CYP3A4MEN1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9061959-B2 Method for manufacturing optically active menthol TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-06-23 — — US claimed
EP-2647616-A1 METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL Takasago International Corporation (JP) 2013-10-09 — — EP claimed
US-20130253228-A1 METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-09-26 — — US claimed
US-6090950-A Chiral hydride complexes ZEELAND CHEMICALS, INC. (US) 2000-07-18 — — US claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 — — US claimed
JP-5059035-A — — None — — JP disclosed
EP-3694864-B1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA INC (US) 2025-03-05 — — EP disclosed
US-11286270-B2 Boronic acid derivatives and synthesis thereof QPEX BIOPHARMA, INC. (US) 2022-03-29 — — US disclosed
US-20200407373-A1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA, INC. 2020-12-31 — — US disclosed
US-10442762-B2 Process for the preparation of carboprost and its tromethamine salt CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT. (HU) 2019-10-15 — — US disclosed
US-10442762-B2 Process for the preparation of carboprost and its tromethamine salt CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT. (HU) 2019-10-15 — — US disclosed
US-20180362457-A1 PROCESS FOR THE PREPARATION OF CARBOPROST AND ITS TROMETHAMINE SALT CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT . (HU) 2018-12-20 — — US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 — — US disclosed
EP-0930312-B1 Production method of optically active amino alcohols JAPAN TOBACCO INC (JP) 2003-01-02 — — EP disclosed
US-6197966-B1 REACTING MESOEPOXIDE WITH AMINE TO FORM 1,3-DIOXEPANE DERIVATIVE; ACID CATALYSIS; RING CONTRACTION TO 1,3-DIOXOLANE JAPAN TOBACCO INC. (JP) 2001-03-06 — — US disclosed
US-6166260-A Tandem reduction and host-guest complexation ZEELAND CHEMICALS, INC. (US) 2000-12-26 — — US disclosed
US-6090950-A Chiral hydride complexes ZEELAND CHEMICALS, INC. (US) 2000-07-18 — — US disclosed
US-6025503-A REACTING OPTICALLY ACTIVE(OR RACEMIC) TITANIUM ALKOXIDE COMPLEXES WITH CHIRAL ACTIVATORS(ESPECIALLY DIOLS) YIELDS NEW TITANIUM COMPLEXES WHICH ARE ENANTIO-SELECTIVE IN C-C BOND FORMING REACTIONS TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-02-15 — — US disclosed
EP-0930312-A1 Production method of optically active amino alcohols Japan Tobacco Inc. (JP) 1999-07-21 — — EP disclosed
JP-H0559035-A SEPARATION OF ISOMER DAICEL CHEM IND LTD 1993-03-09 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10442762-B2 Process for the preparation of carboprost and its tromethamine salt PTGER4, PTGER1, PTGER2 MAPK1 384/4885CYP3A4 171/4885MEN1 2442/4885
US-20200407373-A1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF BTD, BLVRB, BLK MAPK1 2086/4885CYP3A4 471/4885MEN1 853/4885
US-20180362457-A1 PROCESS FOR THE PREPARATION OF CARBOPROST AND ITS TROMETHAMINE SALT PTGER4, PTGIS, PTGER2 MAPK1 529/4885CYP3A4 234/4885MEN1 2609/4885
US-20130253228-A1 METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL MSMO1, GGPS1, MAN1B1 MAPK1 1553/4885CYP3A4 173/4885MEN1 383/4885
US-11286270-B2 Boronic acid derivatives and synthesis thereof BTD, BLVRB, BLK MAPK1 2086/4885CYP3A4 471/4885MEN1 853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.