Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861868 | 1.00 | HPGD (0.34) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4773853 | 1.00 | HPGD (0.34) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29790344 | 0.94 | TAAR1 (0.36) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL29488092 | 0.94 | TAAR1 (0.36) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL478439 | 0.94 | TAAR1 (0.36) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL516227 | 0.94 | TAAR1 (0.36) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL1648239 | 0.93 | GAA (0.36) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL960756 | 0.91 | HPGD (0.37) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL18044488 | 0.89 | PTGS1 (0.37) | ALDH1A1MAPTKDM4EGAAMEP1B | |
| SCHEMBL18044479 | 0.89 | PTGS2 (0.40) | MEN1KMT2AALDH1A1GAAMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570250-B2 | Dibenzosilole monomers and polymers and methods for their preparation and use | Life Technologies Corporation (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180355098-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation | 2018-12-13 | — | — | US | disclosed |
| US-10087280-B2 | Dibenzosilole monomers and polymers and methods for their preparation and use | Life Technologies Corporation (US) | 2018-10-02 | — | — | US | disclosed |
| EP-3215515-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation (US) | 2017-09-13 | — | — | EP | disclosed |
| US-20170247504-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation | 2017-08-31 | — | — | US | disclosed |
| WO-2016073052-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation (US) | 2016-05-12 | — | — | WO | disclosed |
| US-9139869-B2 | Reagents for directed biomarker signal amplification | SIRIGEN INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20140206557-A1 | Novel Reagents for Directed Biomarker Signal Amplification | SIRIGEN INC. (US) | 2014-07-24 | — | — | US | disclosed |
| US-8575303-B2 | Reagents for directed biomarker signal amplification | SIRIGEN GROUP LIMITED (GB) | 2013-11-05 | — | — | US | disclosed |
| US-20110256549-A1 | Novel reagents for directed biomarker signal amplification | SIRIGEN, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110257374-A1 | Novel Reagents for Directed Biomarker Signal Amplification | SIRIGEN, INC. (US) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257374-A1 | Novel Reagents for Directed Biomarker Signal Amplification | RNGTT, CAPG, CD2BP2 | HPGD 2346/4885MEN1 4450/4885KMT2A 4432/4885 |
| US-20110256549-A1 | Novel reagents for directed biomarker signal amplification | RNGTT, CAPG, CD2BP2 | HPGD 2346/4885MEN1 4450/4885KMT2A 4432/4885 |
| US-10570250-B2 | Dibenzosilole monomers and polymers and methods for their preparation and use | DDOST, DDT, DAD1 | HPGD 251/4885MEN1 1168/4885KMT2A 4167/4885 |
| US-20180355098-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | DDOST, DDT, DAD1 | HPGD 251/4885MEN1 1168/4885KMT2A 4167/4885 |
| US-20170247504-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | DDOST, DDT, DAD1 | HPGD 251/4885MEN1 1168/4885KMT2A 4167/4885 |
| US-10087280-B2 | Dibenzosilole monomers and polymers and methods for their preparation and use | DDOST, DDT, DAD1 | HPGD 251/4885MEN1 1168/4885KMT2A 4167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.