Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203818 | 0.81 | MAOB (0.42) | MAOBCYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL8374192 | 0.79 | MAOB (0.50) | MAOBCYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL8374191 | 0.79 | MAOB (0.50) | MAOBCYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL8541497 | 0.79 | MAOB (0.50) | MAOBCYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL8374190 | 0.79 | MAOB (0.50) | MAOBCYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL8413210 | 0.78 | IDO1 (0.47) | CYP1A2IDO1GAATAAR1TDP1 | |
| SCHEMBL8722949 | 0.78 | CYP1A2 (0.45) | MAOBCYP1A2CYP2D6TP53NOS1 | |
| SCHEMBL934485 | 0.76 | TP53 (0.44) | MAOBCYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL8412647 | 0.76 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6HSD17B10CYP2C19 | |
| SCHEMBL2723228 | 0.75 | MAOB (0.46) | MAOBCYP1A2CYP3A4CYP2D6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114247566-A | High-sulfur bauxite desulfurization and desilication flotation collecting agent and integrated flotation method | 中南大学 | 2022-03-29 | — | — | CN | claimed |
| US-20070015755-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2007-01-18 | — | — | US | claimed |
| US-6953850-B1 | Protecting groups for carbohydrate synthesis | ALCHEMIA PTY. LTD. (AU) | 2005-10-11 | — | — | US | claimed |
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | claimed |
| US-20040147745-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-07-29 | — | — | US | claimed |
| EP-1178958-B1 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARM INC (US) | 2004-02-18 | — | — | EP | claimed |
| US-20030096796-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-05-22 | — | — | US | claimed |
| JP-2002539191-A | — | — | 2002-11-19 | — | — | JP | claimed |
| US-6455502-B1 | Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-09-24 | — | — | US | claimed |
| EP-1178958-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-02-13 | — | — | EP | claimed |
| US-6096836-A | OXYGEN CONTAINING AROMATIC CATALYST AND ALUMINUM COMPOUND | KABUSHIKI KAISHA TOSHIBA (JP) | 2000-08-01 | — | — | US | claimed |
| WO-1997006153-A1 | 4-ALKYL-1,3-OXA(THIA)ZOLINE DERIVATIVES, THEIR PREPARATION AND USE FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-20 | — | — | WO | claimed |
| US-5268374-A | Containing both amide and hydroxy groups | ABBOTT LABORATORIES (US) | 1993-12-07 | — | — | US | claimed |
| US-4818749-A | Carboxyalkyl dipeptides and medical use thereof in treating hypertension and congestive heart failure | SCHERING CORPORATION (US) | 1989-04-04 | — | — | US | claimed |
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | claimed |
| EP-0093010-B1 | ALPHA-HYDROXYETHYLPHOSPHINATES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-06-11 | — | — | EP | claimed |
| US-4544652-A | α-Hydroxyethylphosphinates, and their use as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-10-01 | — | — | US | claimed |
| EP-0093010-A2 | Alpha-hydroxyethylphosphinates, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-02 | — | — | EP | claimed |
| US-3953437-A | Process of preparing cephalosporanic acid ester derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-04-27 | — | — | US | claimed |
| US-3935198-A | BY HEATING THE PENICILLIN SULFOXIDE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096796-A1 | Novel compounds and compositions as protease inhibitors | CTRL, SERPINB1, CPN1 | MAOB 1051/4885CYP1A2 2894/4885CYP3A4 1185/4885 |
| US-20040147745-A1 | Novel compounds and compositions as protease inhibitors | CTRL, SERPINB1, CPN1 | MAOB 1051/4885CYP1A2 2894/4885CYP3A4 1185/4885 |
| US-20070015755-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | CTRL, SERPINB1, CPN1 | MAOB 1051/4885CYP1A2 2894/4885CYP3A4 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.