SCHEMBL8722949

SCHEMBL8722949

C[CH]SCCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TAAR1 Q96RJ0 3/20 0.43
SIGMAR1 Q99720 2/20 0.43
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
CYP2A6 P11509 1/20 0.42
HTR2A P28223 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
NOS1 P29475 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2534699 0.78 MAOB (0.46) CYP1A2CYP2D6CYP2C19HSD17B10TAAR1
SCHEMBL11380502 0.77 TP53 (0.42) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL21233204 0.76 SIGMAR1 (0.48) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL7774666 0.76 CYP1A2 (0.45) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL8748239 0.76 TSHR (0.50) CYP1A2CYP2D6CYP2C19ALDH1A1TDP1
SCHEMBL273440 0.72 ALDH1A1 (0.50) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL4185660 0.71 ALDH1A1 (0.55) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL577806 0.71 CYP1A2 (0.76) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL184329 0.70 GPR52 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
Ethane SCHEMBL21049496 0.70 ALDH1A1 (0.61) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114247566-B High-sulfur bauxite desulfurization and desilication flotation collecting agent and integrated flotation method 中南大学 2023-03-21 CN disclosed
CN-114247566-A High-sulfur bauxite desulfurization and desilication flotation collecting agent and integrated flotation method 中南大学 2022-03-29 CN disclosed
WO-1998035982-A1 COMPOUNDS FOR USE IN ADEPT ZENECA LIMITED (GB) 1998-08-20 WO disclosed