Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.63 |
| ▸ | CA7 | P43166 | 5/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.63 |
| ▸ | CA1 | P00915 | 4/20 | 0.63 |
| ▸ | CA2 | P00918 | 4/20 | 0.63 |
| ▸ | CA9 | Q16790 | 4/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056804 | 1.00 | CA12 (0.63) | CA12CA7CA14CA1CA2 | |
| SCHEMBL1882152 | 0.86 | TRPV1 (0.52) | CA12CA7CA14CA1CA2 | |
| SCHEMBL1787681 | 0.84 | CA12 (0.49) | CA12CA7CA14CA1CA2 | |
| SCHEMBL10586238 | 0.83 | CA1 (0.64) | CA12CA7CA14CA1CA2 | |
| SCHEMBL31730518 | 0.82 | CA12 (0.46) | CA12CA7CA14CA1CA2 | |
| SCHEMBL2575691 | 0.82 | CA12 (0.63) | CA12CA7CA14CA1CA2 | |
| SCHEMBL599644 | 0.82 | CA12 (0.63) | CA12CA7CA14CA1CA2 | |
| SCHEMBL31055992 | 0.82 | CA12 (0.67) | CA12CA7CA14CA1CA2 | |
| SCHEMBL31056148 | 0.82 | CA12 (0.67) | CA12CA7CA14CA1CA2 | |
| SCHEMBL29516137 | 0.82 | CA12 (0.63) | CA12CA7CA14CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |