Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA7 | P43166 | 5/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16793863 | 0.91 | LMNA (0.54) | TRPV1CAMK2ALMNAKMT2ATAS1R3 | |
| SCHEMBL16793634 | 0.90 | LMNA (0.50) | TRPV1CA12CA7CA14CA1 | |
| SCHEMBL484798 | 0.88 | LMNA (0.44) | TRPV1CA12CA7CA14CA1 | |
| SCHEMBL31056804 | 0.86 | CA12 (0.63) | TRPV1CA12CA7CA14CA1 | |
| SCHEMBL25347 | 0.86 | CA12 (0.63) | TRPV1CA12CA7CA14CA1 | |
| SCHEMBL14437211 | 0.82 | TRPV1 (0.48) | TRPV1CA12CA7CA14CA1 | |
| SCHEMBL31371415 | 0.82 | TRPV1 (0.48) | TRPV1CA12CA7CA14CA1 | |
| SCHEMBL1787681 | 0.82 | CA12 (0.49) | TRPV1CA12CA7CA14CA1 | |
| SCHEMBL29792352 | 0.82 | TRPV1 (0.46) | TRPV1CA12CA7CA14CA1 | |
| SCHEMBL31424399 | 0.81 | TRPV1 (0.47) | TRPV1CA12CA7CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113660932-B | Phenyl derivatives having pendant alkyl and alkenyl extensions and pharmaceutical compositions comprising the same | 景凯生物科技股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-4389744-A1 | DERIVATIVES HAVING 2,3-DIHYDRO-1H-INDENE OR 2,3-DIHYDROBENZOFURAN MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Yuhan Corporation (KR) | 2024-06-26 | — | — | EP | disclosed |
| EP-4041733-B1 | DERIVATIVES HAVING 2,3-DIHYDRO-1H-INDENE OR 2,3-DIHYDROBENZOFURAN MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORP (KR) | 2024-05-08 | — | — | EP | disclosed |
| US-20230002379-A1 | NOVEL DERIVATIVES HAVING 2,3-DIHYDRO-1H-INDENE OR 2,3-DIHYDROBENZOFURAN MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2023-01-05 | — | — | US | disclosed |
| US-20220411377-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY | 2022-12-29 | — | — | US | disclosed |
| US-20220153687-A1 | PERIPHERAL ALKYL AND ALKENYL CHAINS EXTENDED BENZENE DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2022-05-19 | — | — | US | disclosed |
| EP-3946299-A1 | PERIPHERAL ALKYL AND ALKENYL CHAINS EXTENDED BENZENE DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | Taiwanj Pharmaceuticals Co., Ltd. (TW) | 2022-02-09 | — | — | EP | disclosed |
| CN-113660932-A | Phenyl derivatives with pendant alkyl and alkenyl extensions and pharmaceutical compositions comprising the same | 景凯生物科技股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2021096238-A1 | NOVEL DERIVATIVES HAVING 2,3-DIHYDRO-1H-INDENE OR 2,3-DIHYDROBENZOFURAN MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | WO | disclosed |
| WO-2021081528-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2021-04-29 | — | — | WO | disclosed |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| US-8450483-B2 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-02 | — | — | US | disclosed |
| CN-103038213-A | Process for the preparation of pyrrolines from gamma-nitroketones, use of the gamma-nitroketones as pesticidal agents | BAYER CROPSCIENCE AG | 2013-04-10 | — | — | CN | disclosed |
| EP-2558444-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | Bayer Intellectual Property GmbH (DE) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011128299-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | WO | disclosed |
| EP-2349994-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | disclosed |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | US | disclosed |
| WO-2010043315-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411377-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NOS3, NOS1, NOS2 | TRPV1 1586/4885CA12 3964/4885CA7 2543/4885 |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | DDT, AADAC, AHR | TRPV1 109/4885CA12 4760/4885CA7 3278/4885 |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | CRYAA, ACLY, CRYZ | TRPV1 3492/4885CA12 3174/4885CA7 603/4885 |
| US-20220153687-A1 | PERIPHERAL ALKYL AND ALKENYL CHAINS EXTENDED BENZENE DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | AADAC, ENPP2, ATXN10 | TRPV1 2723/4885CA12 4055/4885CA7 2765/4885 |
| US-20230002379-A1 | NOVEL DERIVATIVES HAVING 2,3-DIHYDRO-1H-INDENE OR 2,3-DIHYDROBENZOFURAN MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | GBA1, GBA2, GAA | TRPV1 1126/4885CA12 1975/4885CA7 2485/4885 |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | CRYAA, ACLY, CRYZ | TRPV1 3492/4885CA12 3174/4885CA7 603/4885 |
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | NOS2, PDXK, GSTK1 | TRPV1 2204/4885CA12 3988/4885CA7 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.