Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 17/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19950462 | 0.93 | WDR5 (0.37) | WDR5 | |
| SCHEMBL18742483 | 0.87 | NPC1 (0.36) | WDR5NPC1ALDH1A1LMNATP53 | |
| SCHEMBL21820655 | 0.83 | NPC1 (0.39) | WDR5NPC1ALDH1A1LMNATP53 | |
| SCHEMBL13344066 | 0.83 | OPRM1 (0.50) | — | |
| SCHEMBL8184527 | 0.82 | CNR1 (0.39) | WDR5NPC1ALDH1A1LMNATP53 | |
| SCHEMBL1542487 | 0.79 | WDR5 (0.41) | WDR5 | |
| SCHEMBL1839257 | 0.79 | OPRM1 (0.34) | WDR5NPC1ALDH1A1LMNATP53 | |
| SCHEMBL3491179 | 0.78 | CA12 (0.39) | WDR5ALDH1A1 | |
| SCHEMBL624106 | 0.77 | CYP1A2 (0.33) | WDR5NPC1ALDH1A1LMNATP53 | |
| SCHEMBL19031018 | 0.76 | WDR5 (0.40) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151640-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |