Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540672 | 1.00 | L3MBTL1 (0.36) | L3MBTL1OPRK1ALDH1A1HPGDDDB1 | |
| SCHEMBL25348951 | 0.82 | L3MBTL1 (0.39) | L3MBTL1OPRK1ALDH1A1HPGDKDM4E | |
| SCHEMBL25348307 | 0.82 | L3MBTL1 (0.39) | L3MBTL1OPRK1ALDH1A1HPGD | |
| SCHEMBL22852087 | 0.70 | CHRM4 (0.37) | — | |
| SCHEMBL25348161 | 0.69 | ACHE (0.51) | L3MBTL1ALDH1A1HPGDKDM4EACHE | |
| SCHEMBL8264784 | 0.68 | CYP1A2 (0.35) | S1PR1 | |
| SCHEMBL25353988 | 0.68 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1HPGDKDM4EACHE | |
| SCHEMBL30540629 | 0.68 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1HPGDKDM4EACHE | |
| SCHEMBL23976198 | 0.67 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL30225223 | 0.67 | S1PR1 (0.31) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696043-A | Heterocyclic compounds, compositions thereof and methods of treatment therewith | 百济神州有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151636-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |