Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 16/20 | 0.74 |
| ▸ | ADCY8 | P40145 | 13/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23160938 | 0.86 | ADCY1 (0.54) | ADCY1ADCY8HTR2BSLC2A1ALDH1A1 | |
| SCHEMBL23188254 | 0.85 | ADCY1 (1.00) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160933 | 0.85 | ADCY1 (0.73) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160969 | 0.84 | ADCY1 (0.61) | ADCY1ADCY8HTR2BSLC2A1 | |
| SCHEMBL23160950 | 0.82 | ADCY1 (0.73) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160940 | 0.81 | ADCY8 (0.68) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160929 | 0.80 | ADCY1 (0.73) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160930 | 0.79 | ADCY1 (0.71) | ADCY1ADCY8HTR2BALDH1A1 | |
| SCHEMBL23160934 | 0.79 | ADCY1 (0.73) | ADCY1ADCY8HTR2BALDH1A1 | |
| SCHEMBL23160941 | 0.79 | ADCY1 (0.71) | ADCY1ADCY8HTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12414949-B2 | Pyrazolyl pyrimidinone compounds and the uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2025-09-16 | — | — | US | disclosed |
| US-20230293523-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230250084-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12414949-B2 | Pyrazolyl pyrimidinone compounds and the uses thereof | CAP1, ADCY1, ADCYAP1R1 | ADCY1 2/4885ADCY8 9/4885HTR2B 1487/4885 |
| US-20230250084-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | CAP1, ADCY1, ADCYAP1R1 | ADCY1 2/4885ADCY8 9/4885HTR2B 1487/4885 |
| US-20230293523-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | CAP1, ADCY1, ADCYAP1R1 | ADCY1 2/4885ADCY8 9/4885HTR2B 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.