Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25351971 | 0.92 | ALOX5 (0.48) | ALOX5PTGES2PTGESHDAC1HDAC6 | |
| SCHEMBL31535158 | 0.92 | ALOX5 (0.48) | ALOX5PTGES2PTGESHDAC1HDAC6 | |
| SCHEMBL24215834 | 0.89 | HDAC1 (0.48) | ALOX5PTGES2HDAC1HDAC6 | |
| SCHEMBL30409440 | 0.89 | HDAC1 (0.48) | ALOX5PTGES2HDAC1HDAC6 | |
| SCHEMBL25352081 | 0.86 | HDAC6 (0.49) | HDAC1HDAC6 | |
| SCHEMBL25351646 | 0.86 | DPP4 (0.48) | HDAC1HDAC6 | |
| SCHEMBL25350410 | 0.86 | HDAC6 (0.45) | HDAC1HDAC6 | |
| SCHEMBL25351906 | 0.85 | HDAC6 (0.44) | HDAC1HDAC6 | |
| SCHEMBL25348959 | 0.85 | HDAC6 (0.58) | ALOX5PTGESHDAC1HDAC6 | |
| SCHEMBL25992736 | 0.83 | HDAC6 (0.43) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-17 | — | — | US | disclosed |
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC6, HDAC1, HDAC3 | ALOX5 4373/4885PTGES2 4622/4885PTGES 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.