Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352502 | 0.86 | CA12 (0.41) | ALDH1A1KDM4ELMNAMAPK1BAZ2B | |
| SCHEMBL25349230 | 0.78 | ACACB (0.38) | — | |
| SCHEMBL25354279 | 0.78 | LIMK1 (0.35) | ALDH1A1 | |
| SCHEMBL25353123 | 0.75 | HRH3 (0.44) | ALDH1A1 | |
| SCHEMBL7373231 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNABAZ2BBAZ2A | |
| SCHEMBL31565403 | 0.71 | MAPK1 (0.42) | ALDH1A1KDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL25351359 | 0.70 | MAP2K1 (0.42) | ALDH1A1KDM4ELMNATSHRHTT | |
| SCHEMBL25353032 | 0.70 | AGBL2 (0.36) | ALDH1A1LMNASMN1; SMN2BAZ2BBAZ2A | |
| SCHEMBL21802602 | 0.69 | MAP2K1 (0.41) | ALDH1A1KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL25351734 | 0.69 | CA12 (0.36) | ALDH1A1KDM4ELMNAMAPK1BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479138-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | Accent Therapeutics, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023154519-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |