Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352198 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL22207271 | 0.82 | MAPT (0.37) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL21822034 | 0.77 | NPC1 (0.46) | ALDH1A1HPGDTSHRNPC1KDM4E | |
| SCHEMBL8395099 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL3975541 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL3977632 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL15358939 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL2418450 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL30501856 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL2359276 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |