SCHEMBL22207271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16495148	0.83	BRD4 (0.40)	MAPTALDH1A1SMN1; SMN2
	SCHEMBL25352201	0.82	ALDH1A1 (0.47)	MEN1KMT2AALDH1A1HPGDNPC1
	SCHEMBL25352198	0.82	ALDH1A1 (0.47)	MEN1KMT2AALDH1A1HPGDNPC1
	SCHEMBL1303947	0.80	ALDH1A1 (0.39)	MAPTMEN1KMT2AALDH1A1HSD17B10
	SCHEMBL16931293	0.78	NPSR1 (0.36)	MAPTMEN1KMT2AALDH1A1HSD17B10
	SCHEMBL16931294	0.78	NPSR1 (0.36)	MAPTMEN1KMT2AALDH1A1HSD17B10
	SCHEMBL3367604	0.78	ALDH1A1 (0.39)	MAPTMEN1KMT2AALDH1A1HSD17B10
	SCHEMBL23907332	0.76	MAPT (0.51)	MAPTMEN1KMT2AALDH1A1HSD17B10
	SCHEMBL22323003	0.76	ALDH1A1 (0.40)	MAPTMEN1KMT2AALDH1A1CYP2D6
	SCHEMBL22207029	0.75	MAPT (0.50)	MAPTMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.