Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428509 | 0.81 | HSPB1 (0.59) | L3MBTL1HSPB1POLBTSHRALDH1A1 | |
| SCHEMBL31498372 | 0.80 | HSPB1 (0.43) | L3MBTL1HSPB1POLBTSHRALDH1A1 | |
| SCHEMBL25356007 | 0.80 | PTGS1 (0.45) | L3MBTL1THRBEPHX2POLBTSHR | |
| SCHEMBL22397221 | 0.75 | THRB (0.41) | L3MBTL1THRBEPHX2ALDH1A1MAPT | |
| SCHEMBL29355127 | 0.75 | THRB (0.41) | L3MBTL1THRBEPHX2ALDH1A1MAPT | |
| SCHEMBL4470732 | 0.73 | THRB (0.51) | L3MBTL1HSPB1THRBPOLBALDH1A1 | |
| SCHEMBL510244 | 0.71 | KMT2A (0.66) | L3MBTL1HSPB1POLBTSHRALDH1A1 | |
| SCHEMBL510359 | 0.71 | KDM4E (0.64) | L3MBTL1HSPB1THRBPOLBALDH1A1 | |
| SCHEMBL21330616 | 0.69 | KMT2A (0.50) | L3MBTL1HSPB1THRBPOLBTSHR | |
| SCHEMBL510942 | 0.69 | MAP4K4 (0.47) | L3MBTL1HSPB1THRBPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |