Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | VRK1 | Q99986 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30193974 | 1.00 | TSHR (0.41) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL30194005 | 1.00 | TSHR (0.41) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL26000660 | 1.00 | TSHR (0.41) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL25359627 | 1.00 | TSHR (0.41) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL26830514 | 0.89 | TSHR (0.40) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL26830512 | 0.89 | TSHR (0.40) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL26001858 | 0.85 | TSHR (0.34) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL26001849 | 0.85 | TSHR (0.34) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL8878642 | 0.82 | TSHR (0.41) | TSHRMEN1KMT2ANPSR1HTT | |
| SCHEMBL16063484 | 0.82 | TSHR (0.33) | TSHRMEN1KMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637438-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| CN-118265704-A | Protoporphyrinogen oxidase inhibitors | 恩科化学公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637438-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, CYP4X1, CBR3 | TSHR 1818/4885MEN1 4860/4885KMT2A 3695/4885 |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, PPIF, CYP4X1 | TSHR 3537/4885MEN1 4689/4885KMT2A 3624/4885 |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PPIF, CYP4X1 | TSHR 3531/4885MEN1 4691/4885KMT2A 3632/4885 |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PPIF, CYP4X1 | TSHR 3537/4885MEN1 4689/4885KMT2A 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.