Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18289621 | 0.89 | HPGD (0.83) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL395942 | 0.89 | HPGD (0.83) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL18289622 | 0.89 | HPGD (0.83) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL4957626 | 0.89 | HPGD (0.83) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL85535 | 0.87 | MEN1 (0.64) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL6841660 | 0.86 | MEN1 (0.59) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL14428282 | 0.86 | HPGD (0.61) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| Fluoride SCHEMBL27503363 | 0.84 | MEN1 (0.62) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL19025562 | 0.84 | MEN1 (0.62) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL9479463 | 0.81 | ALOX12 (1.00) | HPGDALOX12L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |