SCHEMBL85535

SCHEMBL85535

O=[N+]([O-])c1ccc(Br)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
POLB P06746 2/20 0.64
ALDH1A1 P00352 3/20 0.56
HSD17B10 Q99714 2/20 0.56
ACHE P22303 1/20 0.56
LMNA P02545 1/20 0.55
MAPT P10636 2/20 0.53
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
XDH P47989 1/20 0.53
CES1 P23141 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
NLRP3 Q96P20 1/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27503363 0.97 MEN1 (0.62) MEN1KMT2APOLBALDH1A1HSD17B10
SCHEMBL19025562 0.97 MEN1 (0.62) MEN1KMT2APOLBALDH1A1HSD17B10
SCHEMBL2329450 0.93 POLB (0.58) MEN1KMT2APOLBALDH1A1HSD17B10
Cyanide SCHEMBL29151815 0.93 MEN1 (0.58) MEN1KMT2APOLBALDH1A1HSD17B10
4-Bromoaniline SCHEMBL8018592 0.89 ALDH1A1 (0.78) MEN1KMT2APOLBALDH1A1HSD17B10
SCHEMBL27713254 0.89 MEN1 (0.55) MEN1KMT2APOLBALDH1A1HSD17B10
SCHEMBL28959698 0.89 MEN1 (0.55) MEN1KMT2APOLBALDH1A1HSD17B10
Formic Acid SCHEMBL27563395 0.89 MEN1 (0.59) MEN1KMT2APOLBALDH1A1HSD17B10
SCHEMBL28835776 0.89 MEN1 (0.55) MEN1KMT2APOLBALDH1A1HSD17B10
SCHEMBL25354587 0.87 HPGD (0.68) MEN1KMT2APOLBALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3797 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720073-A1 SOLID FORMS OF A MACROCYCLIC FARNESYLTRANSFERASE INHIBITOR AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE MACROCYCLIC COMPOUND AND ITS SOLID FORMS Kura Oncology, Inc. (US) 2026-04-08 EP claimed
CN-119842071-A Conductive polymer material, preparation method and application 北京大学深圳研究生院 2025-04-18 CN claimed
CN-119798106-A Diamine monomer, polyimide, preparation method and application thereof 中山大学 2025-04-11 CN claimed
CN-119680569-A Preparation method and hydrogenation application of hollow IrCu/C nano-catalyst 聊城大学 2025-03-25 CN claimed
CN-119620537-A Photosensitive polyimide photoresist and preparation method thereof 中山大学 2025-03-14 CN claimed
CN-116496173-B High-temperature reversible thermochromic polydiacetylene compound and preparation method and application thereof 中国科学技术大学 2025-03-07 CN claimed
CN-119330839-A Method for preparing p-aminophenylacetylene 金泰旭化学技术(无锡)有限公司 2025-01-21 CN claimed
WO-2024245364-A1 SOLID FORMS OF A MACROCYCLIC FARNESYLTRANSFERASE INHIBITOR AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE MACROCYCLIC COMPOUND AND ITS SOLID FORMS KURA ONCOLOGY, INC. (US) 2024-12-05 WO claimed
CN-116121755-B Chromium metal etching solution for integrated circuit and preparation method thereof 江苏中德电子材料科技有限公司 2024-11-15 CN claimed
CN-118874537-A Catalyst, preparation method thereof and method for preparing aromatic amine compound 厦门大学 2024-11-01 CN claimed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US claimed
US-5130464-A Reaction of aromatic nitro and amine with carbon monoxide in the presence of a catalyst NKK CORPORATION (JP) 1992-07-14 US claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed
US-4375550-A Hydrogenation of halogen-substituted aromatic nitro compounds JOHNSON, MATTHEY & CO., LIMITED (GB) 1983-03-01 US claimed
US-4362645-A Temperature indicating compositions of matter AKZONA, INC. (US) 1982-12-07 US claimed
US-4204078-A REACTING NITROBROMOBENZENE WITH A HYDROXY-ACETYLENE COMPOUND; AMINE SOLVENT AND PALLADIUM COMPLEX CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-05-20 US claimed
US-4170708-A FROM AN AROMATIC NITRO COMPOUND, AN ALCOHOL, AND CARBON MONOXIDE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1979-10-09 US claimed
US-4151165-A USING AN AROMATIC NITRO COMPOUND IN OXYGEN-FREE, AQUEOUS ENVIRONMENT ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-04-24 US claimed
EP-0001479-A2 Process for the preparation of nitrophenylhydroxyacetylene and conversion to nitrophenylacetylene GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-04-18 EP claimed
US-4128588-A PALLADIUM-PHOSPHINE COMPLEX CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-12-05 US claimed