Quinoline

Quinoline

SCHEMBL2535469

CCC.c1ccc2ncccc2c1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.81
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.50
RAB9A P51151 1/20 0.50
CYP3A4 P08684 3/20 0.48
HTT P42858 3/20 0.47
MAPT P10636 3/20 0.47
CYP1A2 P05177 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
CASP1 P29466 2/20 0.47
KDM4E B2RXH2 2/20 0.47
TP53 P04637 2/20 0.47
HSP90AA1 P07900 2/20 0.47
TSHR P16473 2/20 0.47
MEN1 O00255 1/20 0.47
CASP7 P55210 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP2C19 P33261 1/20 0.47
NR4A2 P43354 1/20 0.47
HSP90AB1 P08238 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27960167 0.98 ALDH1A1 (0.77) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL4599170 0.93 ALDH1A1 (0.77) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28292257 0.91 ALDH1A1 (0.74) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL27849601 0.91 ALDH1A1 (0.74) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL3432255 0.91 ALDH1A1 (0.74) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28250556 0.91 ALDH1A1 (0.74) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL4265438 0.91 ALDH1A1 (0.74) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL27467057 0.91 ALDH1A1 (0.74) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL6399465 0.91 ALDH1A1 (0.74) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL8810836 0.91 ALDH1A1 (0.74) ALDH1A1NPC1POLBRAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103665485-B Oil-filled carbon black-filled styrene-butadiene master batch for tire treads, rubber composition and preparation method thereof 中国石油天然气股份有限公司 2016-07-13 CN claimed
CN-103665491-B Oil-extended and carbon black-extended styrene-butadiene master batch, rubber composition and preparation method thereof 中国石油天然气股份有限公司 2016-07-13 CN claimed
CN-102105457-A 5-demethoxyfumagillol and derivatives thereof VERSITECH LTD 2011-06-22 CN claimed
CN-103665491-B Oil-extended and carbon black-extended styrene-butadiene master batch, rubber composition and preparation method thereof 中国石油天然气股份有限公司 2016-07-13 CN disclosed
CN-103665485-B Oil-filled carbon black-filled styrene-butadiene master batch for tire treads, rubber composition and preparation method thereof 中国石油天然气股份有限公司 2016-07-13 CN disclosed
CN-103524970-B Carbon black masterbatch for tire and preparation method thereof 中国石油天然气股份有限公司 2016-06-08 CN disclosed
CN-103665729-B Oil-extended styrene-butadiene rubber containing nano silicon dioxide on surface, composition and preparation method thereof PETROCHINA COMPANY LIMITED (CN) 2016-05-11 CN disclosed
CN-103665484-B Oil-extended styrene-butadiene rubber, composition and preparation method thereof PETROCHINA COMPANY LIMITED (CN) 2016-03-09 CN disclosed
CN-103665486-B Rubber composition containing carbon black masterbatch and preparation method thereof PETROCHINA COMPANY LIMITED (CN) 2016-01-20 CN disclosed
CN-103665471-B Carbon black masterbatch rubber composition for tire and preparation method thereof PETROCHINA COMPANY LIMITED (CN) 2015-10-28 CN disclosed
CN-103524796-B Rubber composition for tire tread and preparation method thereof PETROCHINA COMPANY LIMITED (CN) 2015-08-19 CN disclosed
CN-102731793-B Graft modified rubber and preparation method thereof CHINA NAT PETROLEUM CORP 2013-11-06 CN disclosed
CN-103254351-A Preparation method of carboxyl silicon modified acrylic resin emulsion UNIV SHAANXI SCIENCE & TECH 2013-08-21 CN disclosed
CN-102731854-A Nano silicon dioxide/poly conjugated diene composite emulsion and preparation method thereof CHINA NAT PETROLEUM CORP 2012-10-17 CN disclosed
CN-102731793-A Graft modified rubber and preparation method thereof CHINA NAT PETROLEUM CORP 2012-10-17 CN disclosed
CN-102731874-A Modified rubber and preparation method thereof CHINA NAT PETROLEUM CORP 2012-10-17 CN disclosed
CN-102093504-B Preparation method of high molecular weight salt-resistance and temperature-resistance biopolymer oil displacement agent UNIV HEFEI TECHNOLOGY 2012-09-05 CN disclosed
US-20110240510-A1 OPTIMIZED RELEASE OF BLEACHING SYSTEMS IN LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY 2011-10-06 US disclosed
CN-102105457-A 5-demethoxyfumagillol and derivatives thereof VERSITECH LTD 2011-06-22 CN disclosed
CN-102093504-A High molecular weight salt-resistance and temperature-resistance biopolymer oil displacement agent and preparation method thereof UNIV HEFEI TECHNOLOGY 2011-06-15 CN disclosed