Quinoline

Quinoline

SCHEMBL6399465

CCI.c1ccc2ncccc2c1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.74
POLB P06746 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
CYP3A4 P08684 3/20 0.45
HTT P42858 3/20 0.44
CYP1A2 P05177 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
CASP1 P29466 2/20 0.44
KDM4E B2RXH2 2/20 0.44
TP53 P04637 2/20 0.44
HSP90AA1 P07900 2/20 0.44
MAPT P10636 2/20 0.44
TSHR P16473 2/20 0.44
MEN1 O00255 1/20 0.44
CASP7 P55210 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C19 P33261 1/20 0.44
NR4A2 P43354 1/20 0.44
HSP90AB1 P08238 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL4618171 0.92 ALDH1A1 (0.68) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL28250556 0.91 ALDH1A1 (0.74) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL2535469 0.91 ALDH1A1 (0.81) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL27960167 0.89 ALDH1A1 (0.77) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL4599170 0.89 ALDH1A1 (0.77) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL4619532 0.89 ALDH1A1 (0.85) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL28292257 0.87 ALDH1A1 (0.74) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL27849601 0.87 ALDH1A1 (0.74) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL27467057 0.87 ALDH1A1 (0.74) ALDH1A1POLBNPC1RAB9ACYP3A4
Quinoline SCHEMBL4265438 0.87 ALDH1A1 (0.74) ALDH1A1POLBNPC1RAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111261414-A Quasi-solid electrolyte for dye-sensitized solar cell and preparation method thereof 张礼国 2020-06-09 CN claimed
US-4209418-A CLEANING SOLUTIONS FOR METAL INDUSTRIAL EQUIPMENT UNION CARBIDE CORPORATION (US) 1980-06-24 US claimed
CN-111261414-A Quasi-solid electrolyte for dye-sensitized solar cell and preparation method thereof 张礼国 2020-06-09 CN disclosed
CN-111261414-A Quasi-solid electrolyte for dye-sensitized solar cell and preparation method thereof 张礼国 2020-06-09 CN disclosed
US-9623062-B2 Anti-ageing activity of camphor in fibroblast cell line Jeju National University Industryacademic Cooperation Foundation (KR) 2017-04-18 US disclosed
US-20150374771-A1 ANTI-AGEING ACTIVITY OF CAMPHOR IN FIBROBLAST CELL LINE Jeju National University Industryacademic Cooperation Foundation (KR) 2015-12-31 US disclosed
US-6974865-B2 C3′ -methylene hydrogen phosphonate oligomers and related compounds ISIS PHARMACEUTICALS, INC. (US) 2005-12-13 US disclosed
US-6639061-B1 Rodified oligonucleotides that bear 3'-methylene phosphonate or phosphodiester linkages between constituent monomer nucleoside units ISIS PHARMACEUTICALS, INC. 2003-10-28 US disclosed
US-6414135-B1 PHOSPHONYLATION OF ALKYLNUCLEOSIDE WITH BIS(TRIMETHYLSILYL)PHOSPHONITE IN BASE PRESENCE; CONCENTRATION; ADDING METHANOL SOLVENT; NUCLEASE RESISTANCE; HYBRIDIZATION ISIS PHARMACEUTICALS, INC. 2002-07-02 US disclosed
US-4792644-A ZEOLITE AND QUATERNARY AMMONIUM SALT TOSOH CORPORATION (JP) 1988-12-20 US disclosed
US-4209418-A CLEANING SOLUTIONS FOR METAL INDUSTRIAL EQUIPMENT UNION CARBIDE CORPORATION (US) 1980-06-24 US disclosed