Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21838976 | 1.00 | LMNA (0.41) | LMNAMAOAMAOBESR2ESR1 | |
| SCHEMBL21838974 | 1.00 | LMNA (0.41) | LMNAMAOAMAOBESR2ESR1 | |
| SCHEMBL30079376 | 0.89 | LMNA (0.46) | LMNAMAOAMAOBESR2ESR1 | |
| SCHEMBL25412304 | 0.87 | ACHE (0.40) | LMNAPDE5AMAPTALDH1A1 | |
| SCHEMBL17135569 | 0.83 | KDM1A (0.37) | ALDH1A1 | |
| SCHEMBL28821193 | 0.81 | SPHK1 (0.42) | LMNAMAOAMAOBESR2ESR1 | |
| SCHEMBL19331844 | 0.81 | SPHK1 (0.42) | LMNAMAOAMAOBESR2ESR1 | |
| SCHEMBL19331848 | 0.81 | SPHK1 (0.42) | LMNAMAOAMAOBESR2ESR1 | |
| SCHEMBL28918306 | 0.80 | HTR2C (0.48) | LMNAALDH1A1 | |
| SCHEMBL28918307 | 0.80 | HTR2C (0.48) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |