SCHEMBL25355388

SCHEMBL25355388

CC(C)(C)[Si](C)(C)OCC1C=CCOC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10516509 0.77 DUT (0.33) DUT
SCHEMBL17019777 0.74 DUT (0.34) DUT
SCHEMBL29444723 0.71 DUT (0.31) DUT
SCHEMBL3919020 0.69 TOP2A (0.32)
SCHEMBL17309931 0.69 TOP2A (0.32)
SCHEMBL3917699 0.69 TOP2A (0.32)
SCHEMBL17309920 0.69 TOP2A (0.32)
SCHEMBL24854659 0.69 NFKB1 (0.39) DUT
SCHEMBL3917701 0.69 TOP2A (0.32)
SCHEMBL1712169 0.68 DUT (0.33) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122778-A1 PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS GOSSAMER BIO SERVICES, INC. (US) 2023-06-29 WO disclosed
WO-2023122778-A1 PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS GOSSAMER BIO SERVICES, INC. (US) 2023-06-29 WO disclosed