Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.51 |
| ▸ | PTAFR | P25105 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24434745 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3PTAFR | |
| SCHEMBL25356284 | 0.76 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3PTAFRKDM1A | |
| SCHEMBL19393075 | 0.71 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3GRIA4 | |
| SCHEMBL25354698 | 0.70 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3PTAFRKDM1A | |
| SCHEMBL15629762 | 0.69 | PSEN1 (0.47) | KDM1AKCNH2 | |
| SCHEMBL2693482 | 0.69 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3PTAFRKDM1A | |
| SCHEMBL15629865 | 0.68 | PSEN1 (0.42) | PTAFR | |
| SCHEMBL2693388 | 0.68 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2689197 | 0.68 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25354352 | 0.68 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3PTAFRKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |