Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.54 |
| ▸ | PTAFR | P25105 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25356284 | 0.74 | SLC6A2 (0.56) | SLC6A4SLC6A3SLC6A2PTAFRKDM1A | |
| SCHEMBL2693482 | 0.72 | SLC6A2 (0.72) | SLC6A4SLC6A3SLC6A2PTAFRKDM1A | |
| SCHEMBL2689197 | 0.70 | SLC6A2 (1.00) | SLC6A4SLC6A3SLC6A2DRD1 | |
| SCHEMBL28898650 | 0.70 | SLC6A2 (0.56) | SLC6A4SLC6A3SLC6A2PTAFRKDM1A | |
| SCHEMBL25356229 | 0.70 | SLC6A2 (0.51) | SLC6A4SLC6A3SLC6A2PTAFRKDM1A | |
| SCHEMBL25354888 | 0.70 | SLC6A2 (0.56) | SLC6A4SLC6A3SLC6A2PTAFRKDM1A | |
| SCHEMBL25354352 | 0.70 | SLC6A2 (0.70) | SLC6A4SLC6A3SLC6A2PTAFRKDM1A | |
| SCHEMBL16546365 | 0.69 | SLC6A2 (0.42) | SLC6A4SLC6A3SLC6A2KDM1AMAOB | |
| SCHEMBL16546452 | 0.69 | SLC6A2 (0.42) | SLC6A4SLC6A3SLC6A2KDM1AMAOB | |
| SCHEMBL17548454 | 0.69 | SLC6A2 (0.48) | SLC6A4SLC6A3SLC6A2KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |