SCHEMBL25356997

SCHEMBL25356997

NC(CCCNC(=O)C1CCCCC1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.54
ITGB3 P05106 2/20 0.48
ITGA2B P08514 2/20 0.48
DDAH1 O94760 1/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
OTC P00480 1/20 0.48
DRD2 P14416 2/20 0.45
DRD3 P35462 2/20 0.45
EPHX1 P07099 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
PKM P14618 1/20 0.43
EPHX2 P34913 1/20 0.43
RAB9A P51151 1/20 0.43
GSR P00390 1/20 0.41
CTSL P07711 1/20 0.40
CTSB P07858 1/20 0.40
CTSK P43235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25356994 1.00 NAAA (0.54) NAAAITGB3ITGA2BDDAH1KEAP1
SCHEMBL20704798 0.94 NAAA (0.54) NAAAITGB3ITGA2BDDAH1KEAP1
SCHEMBL15548470 0.94 NAAA (0.54) NAAAITGB3ITGA2BDDAH1KEAP1
SCHEMBL2238409 0.92 OTC (0.51) NAAAITGB3ITGA2BDDAH1OTC
SCHEMBL2238416 0.92 OTC (0.51) NAAAITGB3ITGA2BDDAH1OTC
SCHEMBL16615729 0.87 GSR (0.47) NAAAITGB3ITGA2BDDAH1OTC
SCHEMBL25984019 0.82 NAAA (0.59) NAAAITGB3ITGA2BKEAP1NFE2L2
SCHEMBL25984029 0.82 NAAA (0.59) NAAAITGB3ITGA2BKEAP1NFE2L2
SCHEMBL2237248 0.82 HSD17B10 (0.42) NAAAITGB3ITGA2BDDAH1OTC
SCHEMBL2237255 0.82 HSD17B10 (0.42) NAAAITGB3ITGA2BDDAH1OTC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US claimed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP NAAA 605/4885ITGB3 4109/4885ITGA2B 3548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.