SCHEMBL25358

SCHEMBL25358

O=[N+]([O-])c1ccc(SSc2ccc([N+](=O)[O-])cn2)nc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.62
LMNA P02545 4/20 0.57
TDP1 Q9NUW8 3/20 0.57
KMT2A Q03164 2/20 0.57
MAPT P10636 7/20 0.55
RECQL P46063 1/20 0.55
ALDH1A1 P00352 4/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
HPGD P15428 2/20 0.54
RAB9A P51151 1/20 0.54
PKM P14618 2/20 0.50
NPC1 O15118 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
GAA P10253 1/20 0.48
HTT P42858 1/20 0.48
ADRA2A P08913 2/20 0.47
ADRA2B P18089 2/20 0.47
ADRA2C P18825 2/20 0.47
SLC2A1 P11166 1/20 0.47
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402979 1.00 KDM4E (0.62) KDM4ELMNATDP1KMT2AMAPT
Hydrogen Sulfide SCHEMBL21332206 0.98 KDM4E (0.60) KDM4ELMNATDP1KMT2AMAPT
SCHEMBL21332207 0.96 KDM4E (0.58) KDM4ELMNATDP1KMT2AMAPT
SCHEMBL28888688 0.91 MAPT (0.56) KDM4ELMNATDP1KMT2AMAPT
SCHEMBL29523967 0.91 MAPT (0.56) KDM4ELMNATDP1KMT2AMAPT
SCHEMBL18078274 0.89 MAPT (0.54) KDM4ELMNATDP1KMT2AMAPT
SCHEMBL12161313 0.89 MAPT (0.59) KDM4ELMNATDP1KMT2AMAPT
SCHEMBL13539390 0.89 ALDH1A1 (0.56) KDM4ELMNATDP1KMT2AMAPT
SCHEMBL19456875 0.89 KDM4E (0.55) KDM4ELMNATDP1KMT2AMAPT
SCHEMBL3506729 0.88 KDM4E (0.77) KDM4ELMNATDP1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118703610-A Signal cycle amplification malathion detection method based on aptamer and glucometer 山东师范大学 2024-09-27 CN claimed
CN-118667824-A Signal cycle amplification salmonella detection method based on aptamer and glucometer 山东师范大学 2024-09-20 CN claimed
US-20240132955-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. 2024-04-25 US claimed
CN-117660606-A Methods, compositions, kits and systems for signal enhanced detection of neutralizing targets 哈佛大学校长及研究员协会 2024-03-08 CN claimed
EP-4314324-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS Ultima Genomics, Inc. (US) 2024-02-07 EP claimed
US-20230305006-A1 METHODS, COMPOSITIONS, KITS AND SYSTEMS FOR SIGNAL-ON DETECTION OF NEUTRALIZATION TARGETS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-09-28 US claimed
EP-4225946-A1 METHODS, COMPOSITIONS, KITS AND SYSTEMS FOR SIGNAL-ON DETECTION OF NEUTRALIZATION TARGETS President And Fellows Of Harvard College (US) 2023-08-16 EP claimed
CN-116583608-A Methods, compositions, kits and systems for signal enhanced detection of neutralizing targets 哈佛大学校长及研究员协会 2023-08-11 CN claimed
CN-113337530-B Soluble bIFNT mature peptide gene clone strain, construction method of expression strain and induction expression method of product 西北农林科技大学 2022-12-27 CN claimed
CN-112898580-B Sequencing reagent 安序源生物科技(深圳)有限公司 2022-11-08 CN claimed
EP-1002066-A1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2000-05-24 EP claimed
US-5935862-A DETECTING PRESENCE OF CHEMICAL WARFARE AGENTS BY APPLYING LIQUID SAMPLE TO CHROMATOGRAPHIC ADSORBANT MATERIAL AND DETECTOR AGENT USING MICROCAPILLARY TUBE, FORMING CHROMOGENIC INDICATOR; PORTABLE, SENSITIVE, ACCURATE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1999-08-10 US claimed
WO-1998031734-A1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-07-23 WO claimed
EP-0777966-B1 Disulfide stabilizers for 3-isothiazolones ROHM & HAAS (US) 1998-05-13 EP claimed
US-5725806-A Disulfide stabilizers for 3-isothiazolones ROHM AND HAAS COMPANY (US) 1998-03-10 US claimed
EP-0777966-A1 Disulfide stabilizers for 3-isothiazolones ROHM AND HAAS COMPANY (US) 1997-06-11 EP claimed
US-5510245-A COLORIMETRIC, QUALITATIVE, QUANTITATIVE ANALYSIS OF BETA-HYDROXYBUTYRIC ACID WITH DEHYDROGENASE, NAD, A DISULFIDE SUBSTRATE, A DISULFIDE REDUCTASE AND THIOL-RESPONSIVE INDICATOR DYE; TREATING DIABETES BAYER CORPORATION (US) 1996-04-23 US claimed
US-5326697-A NAD, hydroxybutyrate dehydrogenase, cystine reductase, cystine indicator dye MILES INC. (US) 1994-07-05 US claimed
EP-0464388-A1 Detection assays having chromogenic and nonchromogenic, hypocromogenic, bathochromogenic or hypsochromogenic substrates TECHNICON INSTRUMENTS CORPORATION (a New York corporation) (US) 1992-01-08 EP claimed
US-3937718-A CARBOXYLIC ACIDS, ALCOHOLS, TERTIERY PHOSPHINES, DISULFIDES, SULFENIC ACID ESTER SANKYO COMPANY LIMITED (JA) 1976-02-10 US claimed